English translation for "dna damage response"
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- dna损害反应
Related Translations:
dna电泳: dna electrophoresis
- Example Sentences:
| 1. | Dna damage response
Dna损害反应 | | 2. | Though it has been researched for almost fifty years since discoveried in 1956 , little has been known about the involvement of dna damage response pathways accounting for the radioresistance in this organism
虽然对它的特殊抗性机制有近50年的研究历史，但对于其中的分子机制仍知之甚少。 | | 3. | Certain other types of immune cell seem also to become dysfunctional during aging , and again this may be because they ' ve divided often enough that dna damage responses are kicking in to stop them dividing much more
在老化期间，免疫细胞的某些其他类型似乎也变得功能障碍，这可能又是因为它们分裂太频繁，以致dna损伤反应正在起作用来停止它们分裂更多。 | | 4. | Our structure and function studies on ink , cdk4 , and chk2 proteins shed great light on the mechanisms underlying some cancer diseases , while our enzymological characterizations of human and viral polymerases empower us to further understand the dna damage response and repair at dna level
从相关的特殊功能蛋白质的性质和结构研究，到dna层次的酶学?定，我们已经建立了一套完整的体内和体外研究系统，并将利用蛋白质相互作用的特点，全力发展新一代生物药物。 | | 5. | The protein level of p21 increased lightly from 1 to3 h , then decreased at 6 - 9 h , reached maximum at 24 h after 2gy , it increased from 3 to 24 h exposed tology , and the protein level of p21 associated with cdk2 increased , which did not inhibit the cyclin e / cdk2 kinase activity , because of upregulation of cyclin e and deregulation of p27kipl after irradiation . in contrast to p21 , p27kipl may be a key regulator of cyclin e / cdk2 activity in dna damage responses . hi the ubiquitin - proteasome pathway invovled in regulation of p27kiplexpression in response to ir the ubiquitin - proteasome pathway regulated selective and time - controlled elimination of p27 kipl
与p27ki ” ，表达水平不同， pzi蛋白表达水平在zgy照射后略有增加， 6一gh略有下降，在照后24h达到最大; 10gy照后1一3h开始增加，持续到24h ，并且cycline / cdkz复合物中pzi蛋白结合增多，但cycline / cdkz激酶活性并未受到抑制，除了因ir诱导cydine蛋白表达水平增加外，另一重要的原因就是与pzi同一家族的p27kip ，蛋白表达水平下降，失去了对cycline / cdkz的抑制活性。 | | 6. | On the other hand , the activity and function of p27 kip1 was affected by many physiological agents such as camp , il - 2 , rampamycin . the expression of p27kip1 increased after - irradiationin in the fibroblastoma cells , leading to arrest in gl phase , but its expression markedly decreased after y - irradiation in the nbcc cells , and leaded to arrest in g2 / m phase . several studies have reported that p27 kip1 involved in a much wider range of cellar processes , such as differentiation , apoptosis and migration , the expression level of p27kip1 is key for its function in dna damage responses
另一方面， p27kip ’的活性水平及功能作用，因细胞类型不同而各异，又受多种因素的影响，如一些有丝分裂原camp 、雷帕霉素可以上调p27kip ，的表达，而il一2等则与p27ki ” ‘的表达下降有关，受电离辐射( ir )照射的成纤维细胞瘤及用1 ， 25一二经基d3处理的hela细胞系在gl期均有游离的p27脚‘的积累，细胞周期阻滞在gl期;而在痣癌伽bccs )细胞中， y一射线能诱导p27吻‘表达水平的显著下调，细胞周期阻滞在g2舰期。 |
- Similar Words：
- "dna crosslink" English translation, "dna cyclization" English translation, "dna cytophotometry" English translation, "dna damage" English translation, "dna damage and repair test" English translation, "dna damage surveilance network" English translation, "dna data network address" English translation, "dna database section" English translation, "dna delay mutant" English translation, "dna denaturation" English translation
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